Hesperidin

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Hesperidinraw

English name: Citrus aurantium L Origin: the young fruit of rutaceae poncirus trifoliata, citrus aurantium L or citurs sinensis L osbeck Plant morphology& Physical Property: poncirus trifoliate, citrus aurantium L small arbors The young fruit is spherical, with diameter of 0 3-3 cm Place of origin are Sichuan, Jiangxi, Zhejiang, Guangxi, Hu’nan etc The raw material in Sichuan, named Chuan citrus, while in Jiangxi, named Jiang citrus Collecting and processing: Harvest during May and June, drying in the sun, big ones are cut into two before drying Chemical composition: the peels of citrus contains essential oil and mainly contains flavonoid glycosides etc

HesperidinProducts

Product name: Hesperidin
Synonym:

Hesperetin-7-rhamnoglucoside, Cirmtin, Hesperetin-7-rutinoside
Chemical name: 
(2S)-7-[[6-O-(6-Deoxy--L-mannopyranosyl)--D-glucopyranosyl]oxy]-2,3-dihydro-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one
CAS NO.:520-26-3 
M.S.:

 

M.F. &M. W. :  C28H34O15;    610.55 
Physical Property: thin dendritic-needle-crystal ( PH6-7 precipitation incomes). M.P.: 258-262℃ (soften at 250℃). [α]20D-76℃(C=2,pyridine). 1g soluble in 50L water, soluble in dimethyl formamide and formamide at 60℃, slightly soluble in methanol and heat glacial acetic acid, practically insoluble in acetone, benzene and chloroform, freely soluble in dilute alkali and pyridine.
Plants source: 
Rubiaceae Galium mollugo L. Aerial part. [1] rutaceous citrus medica L. var. sarcodatylis (Noot.) swingle fruit [2] C. tankan hayata fruit [3] poncirus trifoliate L. raf. Fruit [4] Citrus lemon burm. Fruit [5] C. limonia osbeck peel, C.medica L. mature fruit [6] crucifer capsella bursa-pastoris L. medic, full plant with root [7].
Indications: 
1、Anti-inflammatory: take cavy as experimental animal, hesperidin has an improvement effect on eye conjunctival intravascular coagulation of blood cells caused by vitamin C deficiency in cavy and low resistibility of capillary. In other words, hesperidin can enhance the effect of vitamin C. However, it is reported that hesperidin can reduce the coagulation of blood cells. Mixing hespridin with hromobogenic or atherosclerosis to feed cavy, it will prolong survival time of cavy. What’s more, it can promote the growth rate of cavy in vitamin C deficiency by increasing the content of vitamin C in adrenal gland, spleen and white blood cells.
2、Anti-virus: put fibro cells of cavy into 200ug/ml hesperidin for hatching in advance before adding vesicular stomatitis virus, with such handling which can protect cells from virus for about 24hours. Similarly, hatching Hela cells in the same way can prevent influenza virus infection. However, the anti-virus activity of hesperidin can be cancelled by hyaluronidase. 
3、Others: frostbite prevention and rat-eyes-lens-aldehyde reductase prevention.
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