Baicalin

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Baicalinraw

English name: Scutellaria baicalensis Georgi Plant morphology& Physical Property: Scutellaria baicalensisi Georgi belongs to Labiatae Scutellaria Linn , is semi-wild and semi- cultivated variety Its root is herbal medicine, bitter, cold in nature, which can clear heat and dry dampness, purge intense heat and detoxicate, stop bleeding, prevent miscarriage For the main treatment of febrile diseases, upper respiratory infection, cough with lung febrile, damp-heat jaundice, pneumonia, dysentery, hemoptysis, swelling and pain of eye, threatened abortion, hypertension etc Anti-bacterial function is much better than coptis, without any resistance It is mainly produced in Hebei, Henan, Liaoning, Shanxi, Shandong, Inner Mongolia, Helongjiang provinces etc

BaicalinProducts

 

English name: Baicalin
Chemical name: β-D-Glucopyranosiduronic acid,
 5, 6-dihydroxy-4-oxo-2-phenyl-4H-1-benzopyran-7-yl
M.F.&M.W.:C21H18O11        446.35
CAS NO.: 21967-41-9
Physical property: yellow crystalline, M.P.: 223℃, [α]D18+123℃(c=0.2,pyridin-water);UVλmaxMeOH(logε):242(4.12),271(4.50),310(4.22).
Plant source: Scutellaria baicalensisi Georgi of Labiatae Scutellaria Linn. Root[2,3]; S. scordofolia Fisch. (S.galericulata L.) leaf and root[4]; Oroxylum indicum (L.) Vent. Leaf and bark[5];Plantago major L. leaf[6]
Indication: 
1、Anti-inflammatory and anti-allergic reaction: Baicalin has relaxation effect on anaphylactic shrink of cavy in vitro and anaphylactic asthma of overall animals. It also has synergistic effect together with ephedrine and slight antihistamine function. Adding antigen into perfusate in vitro of cavy, it has much more effect than rutin on reduce the releasing of SRS-A and histamine. It also has inhibiting effect on PSA, PCA and cutaneous reaction caused by histamine. Function in inhibiting allergic edema and inflammation, lowering ear capillary permeability of mice, preventing pneumorrhagia caused by infrabar.
2、Anti-bacterial: Baicalin is a part of scutellaria baicalensis with anti-bacterial function. 3% in eye drops are usually applied in treating trachoma, it has similar effect with Rifampicin which is the better medicine to cure trachoma.
3、Diuresis: diuresis effect on rabbits.
4、Cholagogue: increasing the output of bile on dogs and rabbits.
5、Antipyretic: intravenous injection and intraperitoneal injection to rabbits, have antipyretic effect on febrile caused by vaccine or yeast.
6、Depressurization: intravenous injection, intramuscular injection or gavage administration, have depressurization effect on anaesthetic dogs, cats and rabbits.
7、Mitigation: restraining mice’s spontaneous activity.
8、Others: lowering death rate of mice caused by strychnine toxic, increasing 2-5 timed of its LD50 with 10 ug, reducing total cholesterol, free cholesterol and triglyceride fatty acid of experimental rat’s liver.  
9、Clinical use:for the treatment of hepatitis in domestic, magnificent effect on acute jaundice type, acute non-jaundice type and chronic hepatitis.
 
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